Osteoarthritis OA or degenerative joint disease or is the most common form of arthritis. Osteoarthritis occurs over time from wear and tear on the cartilage cushion of the joints. Osteoarthritis can affect any joint in your body, although it most commonly affects joints on your hands, hips, knees and spine.
Osteoarthritis typically affects just one joint, though in some instances, such as with finger arthritis, many joints may be affected. There is no cure for gout but osteoarthritis treatments can Relieve pain and allow you to stay active. Taking measures to actively manage your osteoarthritis may help you gain control over your osteoarthritis pain.
To continue to enjoy the protective benefits of glutathione, individuals must find a way to restore the amount in their bodies to a healthy level. The issue is, direct oral supplementation of glutathione does not work it is broken down in the digestive tract before it can reach the cells. Recently, though, a work around was discovered.
By supplementing with the precursors to glutathione, you allow your body to create its own supplies of the important substance. Osteoarthritis symptoms most commonly affect the hands, hips, knees and spine. Unless you have been hurt or put unusual stress on a joint, it is uncommon for osteoarthritis symptoms to affect your jaw, shoulder, elbows, wrists or ankles.
It is not clear what causes osteoarthritis typically. Researchers suspect that it is a combination of factors, including being overweight, the aging process, joint injury or stress, heredity, and muscular fatigue
Osteoarthritis symptoms often develop slowly and worsen over time. Signs and symptoms of osteoarthritis include:
- Pain in a joint during or after use, or after a period of inactivity
- Tenderness in the joint when you apply light pressure
- Stiffness in a joint, that may be most evident when you wake up in the morning or after a period of inactivity
- reduction of flexibility may make it difficult to utilize the joint
- Grating sensation when you use the joint
- Bone spurs, which seem as hard lumps, may form around the affected joint
- Swelling in Some Instances.
Regan and colleagues at Journal of Osteoarthritis and Cartilage showed us Lone Star Centers that joint fluid from patients with osteoarthritis was characterized by significantly decreased superoxide dismutase levels and significant decreases in glutathione compared to the reference group of knee joints with pain or sub acute injury but macroscopically intact cartilage.
Alonso and colleagues at the Journal of Joint Bone Spine discussed the function of superoxide dismutase in preventing the creation of competitive free radicals that play a role in joint inflammation. There was evidence that antioxidants: glutathione reductive, catalyse, glutathione peroxidise, superoxide dismutase, and Glucose-6-phopshate ruin these free radicals.